A compound found in fiber could play a part in stopping the progression of cancer, according to a new study in mice.
The findings, published in the journal Cancer Prevention Research, highlight the ability of the compound inositol hexaphosphate (also known as IP6) to prevent progression of prostate cancer in mice.
"The study's results were really rather profound. We saw dramatically reduced tumor volumes, primarily due to the anti-angiogenic effects of IP6," study researcher Komal Raina, Ph.D., a research instructor at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of Colorado Cancer Center, said in a statement.
Specifically, researchers found that giving mice this compound -- which is found in high-fiber diets -- prevented new blood vessels from being formed. Without these blood vessels, the tumors were unable to gain the energy needed to grow and progress.
Even though this finding was in animals, other studies in humans have also suggested that fiber has anti-cancer powers. A large review of studies, published in 2011 in the British Medical Journal, showed an association between eating a high-fiber diet and having a lower risk of colorectal cancer, WebMD reported.
For more ways a high-fiber diet can do your body good, click through the slideshow:
Promotes Longevity
Eat fiber, cheat death? A study published last year found that those who met or surpassed the government fiber requirements (again, that's 14 grams per 1,000 calories consumed) were more likely to be alive in a nine-year follow up. In fact, the group that consumed the most fiber had a <a href="http://www.huffingtonpost.com/2011/02/14/eat-fiber-live-longer-now_n_823134.html">22 percent reduced risk of dying from any cause</a> in the course of the follow up.
Maintains Colon Health
While the latest research <a href="http://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/fiber-full-story/index.html#heart">doesn't show a link between dietary fiber and preventing colon cancer</a>, as some early studies suggested, that doesn't mean that a high-fiber diet isn't important for the colon's overall health. A high fiber diet can help to prevent hemorrhoids and diverticuli -- the small "pouches" along the colon -- that can lead to diverticulitis, <a href="http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001303/">a condition in which the pouches become inflamed or infected</a>. It's a common and mild illness, but can lead to complications like a tear in the colon.
Lowers Cholesterol
Soluble fiber can play an important role in reducing low-density lipoprotein or "bad" cholesterol. <a href="http://health.howstuffworks.com/diseases-conditions/cardiovascular/cholesterol/foods-that-lower-cholesterol2.htm">Discovery Health explains</a>: <blockquote>When fiber interferes with absorption of bile in the intestines, the bile is excreted in the feces. To make up for this loss of bile, the liver makes more bile salts. The body uses cholesterol to make bile salts. So in order to obtain the cholesterol necessary to make more bile salts, the liver increases its production of LDL receptors.</blockquote>
Helps Prevent Diabetes
Dietary fiber slows the absorption of sugar in the blood stream, helping to regulate blood sugar levels. That's especially important for those who suffer from diabetes or are susceptible to becoming diabetic. And long-term studies show that, over time, a diet high in fiber can lead to a decreased risk of developing Type 2 diabetes, <a href="http://www.ncbi.nlm.nih.gov/pubmed/18039988?dopt=Citation">especially in high risk groups</a>.
Aids Digestion
Although it may sound counterintuitive, adding bulk and density to one's stool makes bowel movements easier. And fiber is <a href="http://www.mayoclinic.com/health/fiber/NU00033">the best material for the job</a>, adding heft to digested food that would otherwise pass with greater difficulty.
Assists Weight Loss
Dietary fiber can help a person lose weight simply because it takes longer to break down and thus keeps you feeling full for longer. One study <a href="http://www.ncbi.nlm.nih.gov/pubmed/19110020">found that those who ate an apple</a> before lunch consumed 15 percent fewer calories than those who were given applesauce or apple juice before lunch, <a href="http://www.webmd.com/diet/fiber-health-benefits-11/fiber-weight-control">according to WebMD</a>. That's at least in part because the whole apple contains the greatest fiber content.
Prevents Heart Attacks
After several long-term, large-scale studies, a high fiber diet is associated with a reduced risk of coronary heart disease. In fact, in one Harvard study of 40,000 adult men, those who ate a high-fiber diet had a 40 percent reduction in heart disease risk, compared to those who ate low-fiber diets. Research also suggests that fiber can help to <a href="http://www.mayoclinic.com/health/fiber/NU00033">moderate inflammation and reduce blood pressure</a>.
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Source: http://www.huffingtonpost.com/2013/01/13/fiber-prostate-cancer-progression-inositol-hexaphosphate_n_2450487.html?utm_hp_ref=food&ir=Food
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